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Commercial Observer · Capital

Life Sciences Vacancy Near 27% for Three Biggest U.S. Hubs

Via Commercial Observer · October 20, 2026
Compiled by Real Estate Trail Editorial · October 20, 2026

Why this matters

Capital markets activity continues to be defined by the rotation from bank balance sheets to non-bank lenders. Private credit funds have raised record dry powder; banks have tightened CRE underwriting standards for the sixth consecutive quarter. The result is a market where well-sponsored deals clear, and marginal credit pays a meaningful spread to do so. For LPs, the allocation conversation has shifted decisively toward real estate debt, with equity allocations being deployed more selectively into operator-led platforms.

Editorial analysis · Real Estate Trail Editorial

Excerpt from Commercial Observer:
The nation’s largest life sciences hubs are still struggling with elevated real estate vacancy rates and a slowdown in venture capital funding. Despite some pharmaceutical companies making big leasing commitment…
Read the full article at Commercial Observer →

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