Eli Lilly Expands by 82,000 SQFT at Alexandria’s 279 E Grand Avenue in South San Francisco, Peninsula’s Largest Q3 R&D Lease
Why this matters
Commercial real estate continues to digest a multi-year reset in cost of capital. Transaction velocity is below the 2019-2021 trend but improving, cap rates have stabilized across most stabilized property types, and the bid-ask gap has narrowed materially in the past two quarters. Sponsors with permanent capital and operating platforms have an advantage in the current execution environment. San Francisco continues to clear office at the deepest discounts to 2019 basis seen in the cycle, while multifamily fundamentals have stabilized and life sciences in the Peninsula remains active. The next twelve months will continue to reward underwriting discipline and operational sophistication over balance-sheet aggression.
Editorial analysis · Real Estate Trail Editorial
On the RET wire
- The 164th San Francisco story tracked on the wire in October 2026. All San Francisco coverage →
Computed from Real Estate Trail’s own tracked coverage
Eli Lilly expanded its South San Francisco footprint by 82,232 square feet at Alexandria Real Estate Equities' 279 E Grand Avenue, the largest R&D lease signed on the Peninsula in the third quarter, at a time when vac…
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